EChemNews No. 65 | 2007.4.10                             주요내용: 비접촉시 전도도 검출기
 

 

      



비접촉식 전도도 검출기는 무기음이온, 양이온, carboxylic acid, amino acid, 단백질, 항체, 펩타이드 등
organic ion을 포함한 전하를 띤 모든 종의 검출이 기본적으로 가능하며, 주로 모세관전기영동장치
(capillary electrophoresis)에 의해 분리된 물질의 전도도 detecting에 사용됩니다.   


금번에 폐사에서 새롭게 선보이는 contactless conductivity detector는 Agilent, Beckman Coulter, Waters
등에서 공급하는 모세관전기영동장치와 손쉽게 연결하여 사용할 수 있으며, 뿐만 아니라 랩온어칩(lab-on-a-chip)
연구를 위한 microfluidic chip platform을 위해 고안된 제품입니다.

C4D Amp	C4D Head




Plug and play installation
Agilent, Beckmann, Prince사 제품 등 다양한 모세관전기영동장치와 호환
표준 모세관 크기 : 365um OD(외경)의 capillary tubing 사용
     : 365um OD 이상의 모세관을 사용할 경우 또는 chip electrophoresis를 위한 별도의 수정된 C4D Head 공급
데이터 collection을 위해 e-corder와 PowerChrom과 사용할 수 있음.
     : e-corder 상세 정보 보기







Model	Part No.	Description
C4D Amp	EA120	for Capillary Electrophoresis and lab-on-a-chip includes ET120 or ET121 head stage e-corder와 연결하여 사용 가능 ER281 PowerChrom unit와 연결 사용 가능
C4D Detector	ER125	with serial interface includes ET120 or ET121 head stage 별도의 data acquisition system과 사용 가능     (별도의 PowerChrom이나 e-corder 필요 없이 이미 보유하고 있는      소프트웨어 사용 가능)
C4D System Bundle	ER283	경제적인 가격에 시스템 구성 가능 includes ER281 and EA120
C4D Head	ET120	for Capillary Electrophoresis
C4D Microfluidic Platform Head	ET121	for lab-on-a-chip
PowerChrom System	ER281	with I2C expansion
Accelerometer Pod	EP312	with constant current supply




AC excitation: 100 - 1000kHz @ 1 - 50 V (peak to peak)
Range settings: 1 V - 100 µV
Resolution: 16 bits (Chart software), up to 24 bits (PowerChrom software)
Zero offset: 1V




high voltage의 AC파형을 모세관이 지나는 원통형의 전극에 가하고 이를 두 번째 전극이 받아 복조(demodulation)하여
DC signal을 얻게 됩니다.  DC signal의 level은 전극 사이의 용액의 전도도에 따라 결정되고 이로서 전도도를 측정할
수 있게 됩니다.
 




Determination of different classes of amines with capillary zone electrophoresis and contactless conductivity     detection. Xiao Yang Gong, Peter C. Hauser, Electrophoresis, 27, 468?473, 2006.

Determination of chlorhexidine digluconate and polyhexamethylene biguanide in eye drops by capillary     electrophoresis with contactless conductivity detection. Eva M Abad-Villar, Susanne F. Etter; Michael A.     Thiel, and Peter C. Hauser, Analytica Chimica Acta, 561, 133-137, 2006

Evaluation of the detection of biomolecules in capillary electrophoresis by contactless conductivity     measurement. Eva M. Abad-Villar, Pavel Kubán, Peter C. Hauser, Journal of Separation Science, 29,     1031?1037, 2006.

Analysis of electroplating baths by capillary electrophoresis with high voltage contactless conductivity     detection. Ling Zhang, Shokooh S Khaloo, Pavel Kubán, and Peter C Hauser, Measurement Science and     Technology, 17, 3317?3322, 2006.

Enantiomeric separation of underivatized small amines in conventional and on-chip capillary electrophoresis     with contactless conductivity detection. Xiao Yang Gong, and Peter C. Hauser, Electrophoresis, 27, 4375?     4382, 2006.

Rapid electrophoretic separations in short capillaries using contactless conductivity detection and a     sequential injection analysis manifold for hydrodynamic sample loading. Andreas Wuersig, Pavel Kubá,     Shokooh S. Khaloo and Peter C. Hauser,The Analyst, 131, 944?949, 2006.

Detection of Human Immunoglobulin in Microchip and Conventional Capillary Electrophoresis with     Contactless Conductivity Measurements. Eva M. Abad-Villar, Jatisai Tanyanyiwa, M. Teresa      Fernández-Abedul, Agustín Costa-Garcí, and Peter C. Hauser, Analytical Chemistry, 76, 1282?1288, 2004.

Determination of major inorganic ions in blood serum and urine by capillary electrophoresis with contactless     conductivity detection. Qi Jin Wan, Pavel Kubán, Jatisai Tanyanyiwa, Andrea Rainelli, and Peter C. Hauser,     Analytica Chimica Acta, 525,11?16, 2004.

Contactless conductivity detection of selected organic ions in on-chip electrophoresis. Jatisai Tanyanyiwa,     Eva M. Abad-Villar, Peter C. Hauser, Electrophoresis, 25, 903?908, 2004.

Application of a contactless conductivity detector to the determination of inorganic ions in ion     chromatography. Pavel Kubán, Marcel A. Müri and Peter C. Hauser, The Analyst, 129, 82?86, 2004.

On-site simultaneous determination of anions and cations in drainage water using a flow injection-capillary     electrophoresis system with contactless conductivity detection. Pavel Kubán, Miriam Reinhardt, Beat Müller     and Peter C. Hauser, Journal of Environmental Monitoring, 6, 169?174, 2004.

High-voltage contactless conductivity detection of underivatized amino acids in capillary electrophoresis.     Jatisai Tanyanyiwa, Karin Schweizer, and Peter C. Hauser, Electrophoresis, 24, 2119?2124, 2003.

Improved capacitively coupled conductivity detector for capillary electrophoresis. Jatisai Tanyanyiwa,     Benedikt Galliker, Maria A. Schwarz and Peter C. Hauser, The Analyst, 127, 214?218, 2002.

High-voltage contactless conductivity detection of metal ions in capillary electrophoresis. Jatisai     Tanyanyiwa, and Peter C. Hauser, Electrophoresis, 23, 3781?3786, 2002.

 

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